The Most Popular Blockchains in 2025
In 2025, blockchain is no longer a side experiment. It has become a core layer of enterprise infrastructure—just like cloud or databases.
CIOs and CTOs are no longer asking: “Should we use blockchain?”
The real question is: “Which blockchain makes sense for our business case?”
At NOWNodes, we support more than 110 blockchains and process hundreds of millions of RPC requests every month. That gives us a unique vantage point: not just what the market says, but what enterprises actually use in production.
Here’s our look at the most popular blockchains driving enterprise adoption in 2025—based on both market data and our own analytics.
Ethereum: Institutional Anchor
Ethereum remains the standard enterprise blockchain. Its developer ecosystem, compliance tooling, and deep liquidity make it a reliable choice.
Market metrics (2025):
TVL: ~$78B
Daily active addresses: ~600K
NOWNodes data:
28% of all enterprise RPC requests
19% year-over-year growth, driven by tokenization pilots and DeFi integrations
BNB Chain: Enterprise Workhorse
BNB Chain doesn’t get the same headlines as Ethereum or Solana, but it is often the most practical choice. Low fees and high throughput make it ideal for consumer-scale applications such as wallets, neobanks, and loyalty apps.
Market metrics (2025):
~11.5M daily transactions
~4.4M daily active addresses
NOWNodes data:
22% of enterprise RPC requests
In fintech and payments, BNB Chain endpoints see 30% more average traffic than Ethereum
Solana: Performance Leader
When speed is non-negotiable, enterprises choose Solana. Gaming companies, high-frequency finance, and consumer apps rely on its low latency and high throughput.
Market metrics (2025):
80M+ daily transactions
~3.5M daily active wallets
2,000+ active projects
NOWNodes data:
61% year-over-year RPC traffic growth, the fastest of any chain
40% of Solana requests come from gaming and consumer apps
Bitcoin: Bedrock of Trust
Bitcoin is not used for dApps, but for trust and settlement. Enterprises integrate it for treasury, custody, and wrapped assets.
Market metrics (2025):
~$2T market cap
~500K daily transactions
NOWNodes data:
15% of enterprise RPC requests
Mostly related to payments, custody, and compliance reporting
Polygon: Ethereum’s Scalable Twin
Polygon positions itself as Ethereum’s scaling solution. With zkEVM and supernets, it combines compatibility with efficiency.
Market metrics (2025):
~$5.24B TVL
~551K daily active addresses
500+ enterprise and institutional partnerships
NOWNodes data:
18% of enterprise RPC requests
47% year-over-year usage growth, especially in gaming, retail, and tokenization
What the Data Shows
Ethereum still leads, but cost-efficient chains are gaining share
Solana and Polygon are the fastest climbers, favored for scalability and UX
BNB Chain powers high-volume consumer apps
Bitcoin remains the foundation of trust and settlement
The Enterprise Blockchain Stack of 2025
Based on millions of daily RPC calls, the enterprise stack looks like this:
Ethereum + Polygon → core smart contract infrastructure
Solana → user-facing, high-performance apps
BNB Chain → cost-efficient fintech and payments backbone
Bitcoin → treasury and settlement layer
Final Words
The question for enterprises is not “Which blockchain will win?”
It is: “Which combination fits our use case best?”
In 2025, the winners are the chains that deliver trust, speed, and scale—qualities we see reflected in our daily RPC data.
At NOWNodes, we’re proud to power this growth and provide the infrastructure enterprises need to scale Web3 into production.
